Tadalafil vs. vardenafil : Tadalafil (Cialis – brand name) – an oral prescription medication and a reversible phosphodiesterase type -5 (PDE5) inhibitor to treat Erectile Dysfunction (ED). Tadalafil can also treat Benign Prostatic Hyperplasia (BPH), and the other condition namely Pulmonary Arterial Hypertension (PAH).
Vardenafil (generic drug) is another prescription medication that is a member of the drug class - impotence agents. Vardenafil is also one of the commonly sought-after drugs to treat ED. Tadalafil and vardenafil share almost similar properties. The only difference is the effectiveness of each drug. Scientific findings reveal that tadalafil lasts for a longer duration than vardenafil.
Tadalafil vs. vardenafil, which is better?
Vardenafil kicks in faster i.e. in 15 to 30 minutes when compared to tadalafil but does not stay longer. However, even tadalafil has a faster response time when taken as needed. In addition, you can take tadalafil every day to retain its effects round-the-clock. This makes tadalafil unique among other ED pills.
Normally your food intake does not influence the duration of tadalafil’s effect in your system. On the contrary, consuming a high-fat meal does not go well with vardenafil as the medication loses its effect as quickly as it was able to start working i.e. one hour or less.
Which works faster: Tadalafil or Vardenafil?
The difference between tadalafil and vardenafil might be minimal. Both these drugs have a quick response time. Based on your health condition, other medications you take, your tolerance towards side effects, and in particular what you look for in an ED med: a fast-acting drug or a long-lasting one, you can pick the one that suits you the best.
Tadalafil vs Vardenafil: Effectiveness Comparison
When comparing the effectiveness of both the drugs, tadalafil vs. vardenafil, the answer is clear. Tadalafil has an extended effect in your system when compared to vardenafil. Vardenafil is similar to the drug sildenafil in action. The effectiveness of vardenafil will be around 4 to 5 hours.
Side Effects of Tadalafil and Vardenafil
Some common side effects of Tadalafil include headache, muscle pain, nausea, stomach upset, acid reflux, constipation, myalgia, Urinary Tract Infection (UTI), GERD, or respiratory infections. Few reports reveal that patients in the age group of 65 years have suffered from diarrhea more when compared to youngsters.
For vardenafil some common side effects include back pain, muscle pain, headache, stomach upset, flushing or redness on your facial structure. You need to approach your caregiver only if these symptoms prevail for a longer duration.
How long do Tadalafil and Vardenafil last?
Tadalafil and vardenafil vary in the duration they last. The effect of tadalafil remains for more than 36 hours in your system so you can feel its effectiveness throughout. Hence, caregivers recommend only one dose per day.
On the contrary, vardenafil starts to work within few minutes you consume the pill. However, unlike tadalafil, vardenafil’s effect is short-term. It stays in your system for only 4 to 5 hours of time.
Is Tadalafil safer than Vardenafil?
Both drugs tadalafil and vardenafil are safe for use and effective in treating ED in men. But is tadalafil safer? Vardenafil is equally effective as Tadalafil. Both have similar and some common side effects. However, chances are you could even encounter some serious side effects depending on your immunity level; hence, you need to seek medical attention immediately.
Tadalafil vs Vardenafil: A comparison of drug interaction risks
When comparing tadalafil vs. vardenafil, there are a total of 341 drugs that interact with tadalafil. Among those there are:
- Moderate drug interactions account to 208 - 619 brand and generic names
- Major drug interactions stand at 33 amounting to 127 brand and generic names
For vardenafil, there are a total of 508 drugs interactions reported:
- Moderate drug interactions add to 417 for which brand and generic names amount to 1402
- Major drug interactions are 87 - brand and generic names - 275
Cost Comparison: Tadalafil vs. Vardenafil
In comparison - tadalafil vs. vardenafil, as per the per-dose basis, vardenafil is less expensive than tadalafil (Cialis). Some insurance plans may not cover ED pills. Cost-wise comparison of tadalafil vs. vardenafil without any pharmacy discounts or insurance cover:
- Vardenafil is priced in the range of $34 - $40 per pill; vardenafil ODT is available at $34 / pill
- Tadalafil is priced at ~ $45 as an average retail price – i.e., without coupons
Certain insurance plans do not cover tadalafil as well much like vardenafil when taken for ED. However, they accept the coverage when you use it to treat BPH.
Who should take Tadalafil vs who should take Vardenafil?
Who should take tadalafil depends on the person who requires it. Therefore, men mostly use tadalafil to treat ED (sexual impotence). However, tadalafil also treats conditions like pulmonary hypertension in women. Hence, in this case it is a safe medication for women as well.
In addition, vardenafil too treats ED (sexual impotence) in men. Therefore, it is solely an individual preference to choose the ED med based on their specific requirement.
Which ED pill has better user reviews: Tadalafil or Vardenafil?
Data reveals that most patients prefer tadalafil compared to vardenafil. Only few reviewers report a negative effect i.e. 10% reviewers and majority experienced a positive effect i.e. 82%, as per a website data. Vardenafil has an average user ranking. This is again based on data found in a particular website.
Tadalafil or Vardenafil - Vardenafil had an intercourse success rate of 74%, which was average. This is per individual who suffered ED ranging from mild to moderate and who received 20 mg vardenafil. It was for 28% in men who had severe ED.
A clinical pharmacologist with over 12 years of experience in erectile dysfunction research and treatment innovation. Specializes in analyzing the safety, performance, and patient response to ED medications, with a strong commitment to evidence-based medical communication.
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